With the announcement of 1313, its hard to see TFU3 being made anytime soon. While I'm not the biggest fan of the TFU games, I would like to see the story brought to a conclusion. My only major complaints about TFU are the length and minor control issues. They really aren't bad games....
I just hope they don't completely scrap it like they did the KOTOR series. The story has taken a turn which could set up an interesting conclusion. TFU has spawned some pretty likable characters and I would like to see what they end up doing with them.